Carbohydrate receptor-mediated gene transfer to human T leukaemic cells

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Carbohydrate receptor-mediated gene transfer to human T leukaemic cells.

The mucin-type carbohydrate Tn cryptantigen (GalNAc alpha 1-O-Ser/Thr, where GalNAc is N-acetyl-D-galactosamine) is expressed in many carcinomas, in haemopoietic disorders including the Tn syndrome, and on human immunodeficiency virus (HIV) coat glycoproteins, but is not expressed on normal, differentiated cells because of the expression of a Tn-processing galactosyltransferase. Using Jurkat T ...

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ژورنال

عنوان ژورنال: Glycobiology

سال: 1994

ISSN: 0959-6658,1460-2423

DOI: 10.1093/glycob/4.4.429